Southern Illinois University Carbondale

	Doug Smith
Degree	Ph.D., Kansas State University
Position	Professor, Brain and Cognitive Science
Office	77-B, Life Sciences II
Phone	(618) 453-3516
Fax	(618) 453-3563
Email	dcsmith@siu.edu
Biosketch	Douglas C. Smith ( Ph.D, Biopsychology, Kansas State University, 1977) completed two years of postdoctoral training at the University of Illinois-Champaign Urbana where he worked with Dr. Joseph Malpeli on reversible inactivation in electrophysiological experiments in the visual system and Dr. William Greenough investigating neuroanatomical correlates of visual experience and deprivation. He has been at SIUC since 1979. Dr. Smith's current research interests investigate the capacity of vagal nerve stimulation to promote behavioral and anatomical recovery of function following closed head injury or ischemic stroke in the rat. Additional research interests include studies of the neurobiology and neurophysiology of learning and memory in animals and humans. Finally, research in collaboration with colleagues in the medical school investigates the neuropharmacolgy of epileptic seizures and possible means of controlling seizures in experimental rat models of complex-partial epilepsy.
Research Interests	Recovery of Function after Brain Injury Vagal Nerve Stimulation Neurobiology and Neurophysiology of Learning and Memory
Selected Publications	Recent Journal Articles: Roosevelt, R.W. , Smith, D.C., Clough, R.W., Jensen, R.A. & Browning, R.A. (in press). Increased extracellular concentrations of norepinephrine in rat cortex and hippocampus following vagus nerve stimulation. Brain Research. Neese, S.L., Sherill, L.K., Tan, A.A., Roosevelt, R.W., Browning, R.A., Smith, D.C. & Clough, R.W. (in press). Vagus nerve stimulation may protect GABAergic neurons following traumatic brain injury in rats: An immunocytochemical study. Brain Research. Zuo, Y., Smith, D.C. & Jensen, R.A. (in press). Vagus nerve stimulation potentailtes hippocampal LTP in freely-moving rats. Physiology & Behavior. Smith, D.C., Modglin, A.A., Roosevelt, R.W., Neese, S.L., Jensen, R.A., Browning, R.A., & Clough, R.W. (2005). Electrical stimulation of the vagus nerve enhances cognitive and motor recovery following moderate fluid percussion injury in the rat. Journal of Neurotrauma, 22 (12), 1485-1502. Smith, D.C., Tan, A., Duke, A., Neese, S. L., Clough, R.W., Browning, R.A. & Jensen, R.A. (2006). Recovery of function following vagus nerve stimulation initiated 24 hours post-fluid percussion brain injury. Journal of Neurotrauma, 23, 1549-1560. Hoane, M.R., Tan, A., Pierce, J.L., Anderson , G.D., & Smith , D.C. (2006). Nicotinamide treatment reduces behavioral impairments and provides cortical protection following fluid percussion injury in the rat, Journal of Neurotrauma, 23, 1537-1548.
Teaching	Undergraduate Psychology Courses: Effects of Recreational Drugs (Psyc 222) Introduction to Neuroscience (Psyc 302) Recovery of Function Following Brain Damage (Psyc 416)